Triple quadrupole mass spectrometry (TQMS) is a versatile tool for quantitative analysis. Experience the excellent performance and robustness of Shimadzu’s LCMS-TQ instruments, which offer a choice of speed, sensitivity and resolution to meet the demands of high-throughput routine analysis and/or more specialized applications. 

Compare Shimadzu’s triple quadrupole LC-MS/MS systems below. 

Triple Quadrupole LC-MS/MS Comparison

  LCMS-8060RX LCMS-8050RX LCMS-8045RX
Features The LCMS-8060RX builds on the exceptional sensitivity and UF capabilities of the LCMS-8060NX and adds even more robustness without compromising sensitivity. Engineered to deliver excellent sensitivity the LCMS-8050RX further extends the performance of the LCMS-8050 to meet the ever-changing needs of any LC-MS/MS laboratory. Designed for rugged, routine LC-MS/MS analysis with the optimal balance of cost, sensitivity and performance now enhanced with greater robustness and easier to use.
Sensitivity (S/N) 5 4 3
Scan Speed 5 5 5
Ionization Unit Compatibility ESI      
APCI
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sample
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DUIS*1)
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Heated-ESI
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sample
Heated-ESI with IonFocus
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sample
sample
Micro-ESI
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Probe-ESI
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sample
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Measurement Mode Q1 Scan/SIM
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Q3 Scan/SIM
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sample
sample
MRM
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sample
sample
Precursor ion scan
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sample
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Product ion scan
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sample
sample
Neutral loss scan
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Synchronized Survey Scan™*2)
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Collision Cell UFsweeper™*3) III UFsweeper III UFsweeper II
QP guard *4)
sample
   
  LCMS-8060RX LCMS-8050RX LCMS-8045RX
  • DUIS: The dual ion source continuously performs both electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI).
  • Synchronized Survey Scan: Synchronized Survey Scan (SSS) automatically performs a product ion scanning whenever a pre-set survey scan threshold is exceeded.
  • UFsweeper: UFsweeper is a unique technology that delivers unparalleled efficiency and speed. UFsweeper accelerates ions out of the collision cell by forming a pseudo-potential surface.
  • QP guard: Reduces contamination of the quadrupole rod by applying voltage to the multi-pole and preventing unwanted ions from entering the quadrupole rod.
  LCMS-8060NX LCMS-8060 LCMS-8050 LCMS-8045
Features On top of the architecture of the LCMS-8060, it adds flexibility in optimizing parameters to achieve unsurpassed sensitivity. New ion optic components all increase robustness without compromising on a high ion transmission rate. A new vision in sensitivity. It is suitable for drug discovery, manufacturing, clinical research, food safety, environmental, or drugs-of-abuse analysis. The first mass spectrometer to achieve a scan speed of 30,000 u/sec and 5 msec polarity switching time. It boasts the ideal balance of good data quality, high throughput and affordability for a wide range of challenging and routine applications. Designed specially for robust data acquisition with best-in-class sensitivity. It withstands long periods of continuous operation in laboratories in demand of reliable data.
Sensitivity (S/N) 5 5 4 3
Scan Speed 5 5 5 5
Ionization Unit Compatibility ESI        
APCI
sample
sample
sample
sample
DUIS*1)
sample
sample
sample
sample
Heated-ESI
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sample
sample
 
Heated-ESI with IonFocus
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Micro-ESI
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sample
sample
sample
Probe-ESI
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sample
sample
sample
Measurement Mode Q1 Scan/SIM
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sample
sample
sample
Q3 Scan/SIM
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sample
sample
sample
MRM
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sample
sample
sample
Precursor ion scan
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sample
sample
sample
Product ion scan
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sample
sample
sample
Neutral loss scan
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sample
sample
sample
Synchronized Survey Scan™*2)
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sample
sample
sample
Collision Cell UFsweeper III*3) UFsweeper III*3) UFsweeper III*3) UFsweeper II*3)
  LCMS-8060NX LCMS-8060 LCMS-8050 LCMS-8045
  • DUIS: The dual ion source continuously performs both electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI).
  • Synchronized Survey Scan: Synchronized Survey Scan (SSS) automatically performs a product ion scanning whenever a pre-set survey scan threshold is exceeded.
  • UFsweeper: UFsweeper is a unique technology that delivers unparalleled efficiency and speed. UFsweeper accelerates ions out of the collision cell by forming a pseudo-potential surface. 
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