LabSolutions Insight Biologics

Software for Oligonucleotide Sequence Characterization

A Dedicated Workspace for Oligonucleotide Characterization

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LabSolutions Insight Biologics is a dedicated software platform for oligonucleotide characterization using single quadrupole (SQ) mass spectrometers, the LCMS-9030 or LCMS-9050 quadrupole time-of-flight type (Q-TOF) mass spectrometer or MALDI mass spectrometers. Main product and impurity identification includes several core editors for sequence, nucleotides, linkers, ribose and base modifications. Together with processing and integration for target modifications, Insight Biologics is a comprehensive workspace for data review, processing, and reporting.

Insight Biologics provides an easy method to input sequence information, configure target modifications, and set data analysis parameters. Using sequence information, Biologics comprehensively identifies chain length differences, nucleotide gaps, modifications, conversions, adducts, and other impurities. Q-TOF Data Dependent Acquisition (DDA) records MS and MS/MS spectra. MS spectra are used to identify the molecular weights of impurities, and corresponding MS/MS fragment spectra are used to confirm sequences. Visual displays of sequence coverage enhance the confidence of identifications. Seamless processing and reporting with audit trail support make Insight Biologics a comprehensive solution for oligonucleotide characterization.

LabSolutions Insight Biologics is all-in-one LabSolutions series software. After measurements with LabSolutions, the data analysis is implemented automatically with the specified parameters, so when the measurements are started, everything up to the display of the analysis results is performed seamlessly.

Capable of Analyzing LCMS-SQ, LCMS-QTOF, and MALDI Data

In addition to QTOF, LabSolutions Insight Biologics can analyze SQ and MALDI data. When QTOF is used, high-accuracy results are obtained, while SQ and MALDI can be used for applications where convenient measurement is prioritized. In process management, everything from the establishment of efficient processes to productivity improvements can be implemented. In addition, it can be used in research and development in a variety of fields. The data analysis parameters can be conveniently deployed even in workflows with different instruments, so there is no need to remember new operations.

Capable of Analyzing LCMS-SQ, LCMS-QTOF, and MALDI Data

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Latest Webinar

2024-03-20

Towards the Future of Biopharma: Insights into Oligonucleotide Therapeutics

In this webinar, we showcase state-of-the-art solutions that support the entire workflow employed by Contract Drug Manufacturing Organizations (CDMOs), from R&D to validation and manufacturing. Get valuable insights into biopharmaceutical drug development and delve into the capabilities of our solutions, including our Nexera XS inert system, LCMS-9050 QTOF, and the latest LabSolutions Insight Biologics software.

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