• Ultra-low baseline pulsation
• High flow rate accuracy and gradient repeatability
• Consistent peak retention times - all day, every day
Boost Lab Efficiency with Nexera HPLC!
Ultra High Performance Liquid Chromatograph
Maximum uptime. Lowest hplc carryover. Industry-leading repeatability.
Check out all the reasons why the Shimadzu Nexera 40 Series is quickly becoming the world’s most requested HPLC system
At Shimadzu, we understand that HPLC systems have one job—to process as many samples as possible, day after day, while maintaining the accuracy and repeatability you need. All with minimal downtime and maintenance needs. That’s what the Nexera 40 Series is designed to do—with special features you won’t find anywhere else.
To create the Nexera system, we started with the field-proven pumps, autosamplers and detectors that have made Shimadzu the most trusted name in LC. Then we enhanced it by adding industry-leading efficiency and time-saving technologies. So it’s fast, it’s easy to use and maintain, and it helps you get more done. That’s why lab managers are choosing Shimadzu HPLC systems for their operations.
Critical HPLC Components You Know and Trust
Shimadzu pumps, autosamplers and detectors have been the gold standard for accuracy and repeatability for decades.
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• Ultra-low carryover (<0.0003%)
• Ultra-fast injection every 6.7 seconds
• High precision and great linearity
• Large sample capacity with single device
• Automated pre-treatment functions (co-injection, dilution, reagent addition, and overlap injections) -
• Wide linear dynamic range
• Stability - repeatable results
• Low noise - high signal to noise for high-sensitivity analyses
Features
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Nowhere is time more important than in a busy analytical lab. The opportunities to shave critical minutes and seconds from the processes you perform every day are all around you. The Nexera system helps you take advantage of them all. The result is days and even weeks of extra time savings for your operation each year.
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Intelligent Peak Deconvolution Analysis (i-PDeA) is a data analysis technique that extracts a single peak from co-eluted peaks and quantitates it by exploiting the differences in spectra between each compound. -
Learn about all the features of the Nexera Series: Analytical Intelligence, Efficiency, Speed and Carryover -
The LabSolutions software platform is Shimadzu’s ULMS systems. It provides a single, easy to use interface for multiple types of Shimadzu instruments. LabSolutions ULMS provides extremely efficient laboratory workflows while still providing the high level functionality and data management that our customers have come to expect from all Shimadzu products. -
Latest Webinar
Videos
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How To Manually Prime a Shimadzu LC 40 Pump
This video demonstrates the proper procedure to manually prime the pump on a Shimadzu LC 40 instrument.
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Nexera series
- Experience New Benchmarks - The Nexera series is a family of HPLC systems that marries AI and IoT enhancements to set new industry
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Nexera series Concept Video
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How To Clean or Replace the Check Valves on a Shimadzu LC-40 Series Nexera Pump
In this video, you will learn how to safely clean or replace the check valves on a Shimadzu LC-40 Series Nexera pump.
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How To Replace the Plunger Seal on a Shimadzu LC-40 Series Nexera Pump
This video shows the proper procedure to safely remove and replace the plunger seal on the Shimadzu LC-40 Series Nexera pump.
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Enhancing Lab Performance with Nexera™ Auto-Recovery & Auto-Diagnostic Features
Regular maintenance is crucial to keep your HPLC and UHPLC instruments running at peak performance and getting accurate results. Shimadzu's Nexera UHPLC Series features auto-diagnostic and auto-recovery features that automatically detect abnormal pressure fluctuations, preventing data loss and wasted samples.
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One minute in Shimadzu
What can we do in one minute? You may feel like one minute is too short for anything to really happen. In this short video, we will introduce how Shimadzu's analytical instruments can perform high-speed analysis and bring value to our customers in one minute.
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Ensuring Data Accuracy & Reliability with Smart Flow Control
UHPLC and HPLC analysis require careful management of flow rate to reduce maintenance costs and protect valuable columns. Shimadzu’s Smart Flow Control helps protect expensive analytical columns and ensures you get accurate, reliable results you can trust. This intelligent start-up feature slowly increases the flow rate to avoid damaging critical equipment.
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Real-Time Mobile Phase Monitoring — Nexera™ UHPLC Series
Making sure you have sufficient mobile phase in your HPLC or UHPLC systems is critical to keeping your lab running smoothly. Shimadzu’s Nexera UHPLC Series enables real-time monitoring of mobile phase levels to ensure maximum equipment uptime.
News / Events
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PITTCON 2025
March 1-5
Boston, MA -
HPLC 2024
July 20-25
Hilton Denver City Center, Denver Ballroom
Denver, Colorado
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Shimadzu Scientific Instruments Opens R&D Center
These forward-focused R&D centers will enable us to closely collaborate with customers and stakeholders to develop products that meet tomorrow’s analytical laboratory needs and swiftly deliver these solutions to the marketplace.
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National American Chemical Society (Spring) 2024
March 18-20
Ernest N. Morial Convention Center
New Orleans, Louisiana
Booth # 2931
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Shimadzu Scientific Instruments and Telescope Innovations Initiate Technology Partnership
The partners aim to integrate SSI’s High-Performance Liquid Chromatography (“HPLC”) systems with Telescope’s flagship product, the DirectInject-LC.
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New Nexera™ XS inert UHPLC System Eliminates Challenges of High-Concentration Mobile Phases to Achieve High Sensitivity and Reliability
Awards
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Red Dot Design Awards for Product Design 2019
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GOOD DESIGN
Sustainability initiatives
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3 Good health and well-being
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2 Zero hunger
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6 Clean water and sanitation
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Eco Products Plus Certified products