LCMS-8060 Triple Quad LC-MS/MS - Options

Triple Quadrupole Mass Spectrometer

Newly Designed Ionization Unit

Designed without cables or tubes, removing the new ionization unit is simple: release a one-touch lever to open the unit and lift it out. In addition, no tools are needed to detach the needles fitted in APCI and DUIS units, allowing for easy maintenance.

IonFocus unit

A newly-developed ESI probe with focus electrodes introduces ions into the mass spectrometer more effciently, while expelling contaminants to reduce noise and provide more stable data. In addition, an improved heat-assist design promotes the ionization of a wide range of compounds. (Patented technology.) A new heat-assisted design improves the desolvation efficiency and dramatically enhances the sensitivity for challenging molecules such as steroid hormones.

Superior robustness

The excellent robustness of the LCMS-8060NX can be seen most clearly during consecutive analyses of samples of biological origin that tend to contaminate instruments. We performed consecutive analyses of human blood plasma spiked with alprazolam on the LCMS-8060NX and plotted the resulting area values and area ratios (internal standard material: alprazolam-d5). To evaluate the robustness under even more demanding conditions, we performed a total of 15,000 consecutive analyses without using valves to remove impurities. As shown in the data below, the results were extremely stable, with an area value reproducibility of 1.79 %RSD and an area ratio reproducibility of 1.71 %RSD. This demonstrates the excellent stability of results with the LCMS-8060NX even during consecutive analyses of samples with large amounts of contaminants such as urine and blood plasma.

Results from Consecutive Analyses of Alprazolam-Spiked Human Blood Plasma

LC/MS/MS Method Package and MRM Library

Designed for fast set-up in a range of support packages from pesticides to metabolic enzymes in wheat.

	Description
Method package	Residual Pesticides
	Veterinary Drugs
	Water Quality Analysis
	Drugs of Abuse
	Rapid Toxicology Screening
	Primary Metabolites
	Lipid Mediators
	Cell Culture Profilling
MRM Library	Metabolic Enzymes in Yeast