Nexera HPLC/UHPLC Autosampler - SIL-40CX3

Expand your chromatographic precision and accuracy with our highest performing autosampler. This new design gives you the fastest reproducible injections with improved sample cooling. Maximize your confidence in low-level quantitation with injection volumes down to 0.1 µL and ultra-low carryover with external needle and multi-solvent internal rinsing as standard features. The SIL-40C X3 is ideal for sub-2µm FPP or SPP columns with its pressure rating of up to 130 MPa (1300 bar). This autosampler is paired with LC-40D X3 or LC-40B X3 UHPLC pumps. Short cycle times increase sample throughput for high-efficiency separations while maintaining wide injection volume flexibility for UHPLC applications.

• Features a needle in the flow path design to minimize carryover.
• Standard sample loop (50 µL), an optional sample loop (2000 µL) and a fixed-loop configuration (5 or 20 µL) are available.
• Total injection method: 0.1 to 50 µL in increments of 0.1 µL from 0.1 to 9.9 µL, and 1 µL from 10-50 µL.
• Performs sample pretreatment including dilution, reagent addition, co-injection of samples, stacked injection, and overlapped injection.
• Temperature control from 4 to 45°C (± 2°C accuracy,) with a forced air cooling mechanism to reduce condensation.
• Industry-leading cycle time of ≤ 7 seconds.
• Injection volume repeatability: RSD ≤1.0% for 0.5-0.9 µL, RSD ≤0.5% for 1.0-1.9 µL, RSD ≤0.25% for 2.0-4.9 µL, RSD ≤0.15% for injections ≥5.0 µL.
• Injection volume accuracy of ±1% for 5 μL injections (n=20).
• Carryover performance: 0.0015% (no needle rinsing) and 0.0003% (with rinse).
• Equipped with both a static rinse port and an active rinse pump to rinse the outside of the needle before and/or after aspirating sample.
• A 3-solvent internal rinse option is available to clean the inside of the needle and loop after sample injection to further reduce carryover.
• A dual injection mechanism can be installed for high throughput operation or complementary analysis.
• Maximum pressure rating of 130 MPa (1300 bar).