Boost LCMS-9030 Performance: Precision Analysis Upgrades

High-resolution, accurate-mass (HRAM) mass spectrometers (MS) are a class of MS instrumentation with capability to resolve complex sample matrix and to allow identification of compounds by measuring their accurate masses. In particular, those coupled to liquid chromatograph (HRAM LC/MS) have been used extensively for structural elucidation of unknown compounds primarily in chemical industry (impurity analysis) and biological researches (proteomics, metabolomics, lipidomics), but also increasingly in forensic science, food safety and environmental testing. Given the recent reduction of instrumentational cost, it will not take many more years until HRAM analysis becomes a versatile tool for all industries and researches.

The webinar describes various metrics that are relevant to statistical interpretation of MMA, which explain why mass resolution of 30,000 is more than sufficient for mass measurement at sub-ppm accuracy. Using the Shimadzu LCMS-9030 quadrupole time-of-flight MS, the rationale and strength of instrument stability for consistently achieving sub-ppm MMA has been demonstrated in small molecules.

The LCMS-9030 quadrupole time-of-flight (Q-TOF) mass spectrometer integrates the world' s fastest and most sensitive quadrupole technology with TOF architecture. A product of Shimadzu's engineering DNA, speed and effortless performance enable the LCMS-9030 to address qualitative and quantitative challenges with genuine confidence and ease.

Leachables and extractables pose risks to food contact materials. Shimadzu's Q-TOF mass spectrometer provides fast, reliable analysis of these contaminants in food products.

This video describes the simple steps it takes to easily process QTOF or QQQ data using the library search function within LabSolutions Insight, Shimadzu’s data processing software. Cleary demonstrated is how to load a batch, set up flags, search within a library and report the final result.