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LC/MS Multiplexing
In a typical drug development cycle, the number of candidates that need to be tested in early stages can be in the thousands. The ability to quickly determine the active members of a drug class under investigation can have a great effect on the time spent in development. Having the right tools to select hits and eliminate misses can save days, weeks or even months in the effort to deliver new therapeutics.
Newly developed Nexera QX and associated QX Solutions software provides an automated single point of control for up to 4 UHPLC streams and the mass spectrometer for a multiplexed workflow. QX Solution simplifies valve switching, gradient control and injection timing and can execute automatic flushing from dedicated pumps to reduce autosampler and column carryover to a minimum. Specifically designed for the high-throughput laboratory, the system features the easy import of spreadsheet sample batches.
Shimadzu is known for providing rugged, clean, and fast autosampler solutions for even the most demanding UHPLC analysis. No matter the scale of your throughput needs, we have an autosampler solution to fit your LC or LC-MS workflow. Our Nexera Plate Changer has the flexibility to accommodate up to 14 micro-titer plates (MTP) per unit, with up to three units being connected to a single autosampler for a 44-plate total capacity.
Featured Solutions
Ultrafast Multiplex LCMS System - Nexera QX
The Nexera QX Multiplex LC-MS/MS System uses multiple, alternating sample introduction streams for continuous operation of the mass spectrometer to significantly increase laboratory throughput and profitability.
Nexera™ QX: Improving the Efficiency of Routine LC-MS/MS Assay with Multiplex UHPLC Platform
For many modern analytical laboratories, high-throughput analysis is pivotal. LC-MS/MS shows enormous capabilities for increasing sample throughput by monitoring multiple analytes simultaneously. Over the duration of the method, the time frames used for injection, column wash, and column equilibration time frequently represent a waste of time which negatively affects the throughput of the analysis. A multi-channel LC configuration can provide the capability to maintain the same analytical conditions while increasing sample throughput by reducing the detector idle time. The Nexera QX, a two-channel system coupled with a triple quadrupole MS detector, provides reliable and robust results running an LC-MS/MS method on two parallel flow lines and contributes to effortless usability in increasing the overall analytical throughput.
Ultra-High Speed LCMS System for Multiplex Analysis - Nexera MX
Double your sample throughput and simplify batch analysis with the Nexera MX multiplex LC/MS system. The MX Dual Stream Technology (MX-DST) system allows near-continuous data acquisition and halves analysis times for batch analysis compared to conventional LC/MS analysis.
News / Events
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AAPS Pharm Sci 360 2024
October 21-23
Salt Palace Convention Center
Salt Lake City, Utah
Booth #2107
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ASMS (American Society for Mass Spectrometry) 2024
June 2-6
Anaheim Convention Center
Anaheim, California
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Shimadzu Scientific Instruments Opens R&D Center
These forward-focused R&D centers will enable us to closely collaborate with customers and stakeholders to develop products that meet tomorrow’s analytical laboratory needs and swiftly deliver these solutions to the marketplace.