1 Various Problems That Can Occur Due to Air in Mobile Phases

To reconfirm the importance of degassing mobile phases, the following shows an example of problems that can occur due to air in the mobile phase. These problems can be resolved through appropriate degassing.

These problems can be roughly categorized as problems related to the formation of air bubbles and problems related to dissolved air, with no air bubbles formed.

We also receive reports of dissolved oxygen causing problems, such as the oxidation of sample components, compounds in the mobile phase, and the solid phase, but regrettably, that discussion is not within the scope of this article.